After the Sack of Rome in 1527 and the death of Leo X, artistic patronage in Rome slackened. Federico Gonzaga sent Baldassare Castiglione to procure Giulio to execute paintings and architectural and engineering projects for the duchy of Mantua. His masterpiece of architecture and fresco painting in that city is the suburban Palazzo Te, with its famous illusionistic frescos. Another product of this era is this painting of the birth of Bacchus, now at the Getty Museum.
Giulio Romano: The Birth of Bacchus, c. 1530.